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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MYO1H
All Species:
27.58
Human Site:
S587
Identified Species:
50.56
UniProt:
Q8N1T3
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q8N1T3
NP_001094891
1032
119037
S587
S
L
L
E
T
L
I
S
K
E
P
S
Y
I
R
Chimpanzee
Pan troglodytes
XP_509352
1105
127217
S616
S
L
L
E
I
L
I
S
K
E
P
S
Y
I
R
Rhesus Macaque
Macaca mulatta
XP_001097258
647
75756
A246
E
H
L
R
V
R
R
A
G
F
A
Y
R
R
K
Dog
Lupus familis
XP_537765
1636
184093
S746
Q
L
V
E
I
L
K
S
K
E
P
A
Y
V
R
Cat
Felis silvestris
Mouse
Mus musculus
Q9D6A1
958
109974
P557
E
L
E
N
R
R
R
P
P
T
V
G
T
Q
F
Rat
Rattus norvegicus
Q63355
1044
119793
S598
Q
L
V
E
I
L
R
S
K
E
P
A
Y
I
R
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508359
1162
132441
S635
S
L
M
D
I
L
M
S
K
E
P
S
Y
I
R
Chicken
Gallus gallus
Q5ZLA6
1028
118889
S582
K
L
M
E
I
L
M
S
K
E
P
S
Y
I
R
Frog
Xenopus laevis
A0MP03
1028
118817
S582
K
L
M
E
I
L
M
S
K
E
P
S
Y
V
R
Zebra Danio
Brachydanio rerio
A5PF48
1026
118045
S581
K
L
M
D
I
L
M
S
K
E
P
S
Y
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q23979
1035
118971
C587
N
L
M
D
I
L
M
C
K
E
P
S
Y
I
R
Honey Bee
Apis mellifera
XP_394436
1060
122678
G609
N
L
V
E
I
L
M
G
K
E
P
S
Y
I
R
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7SDM3
1235
136290
K597
A
L
V
D
T
L
M
K
C
Q
P
S
Y
I
R
Conservation
Percent
Protein Identity:
100
89.4
61
39.5
N.A.
82.1
60
N.A.
69.6
62.3
60.1
59.1
N.A.
49.7
49.2
N.A.
N.A.
Protein Similarity:
100
90.2
61.8
50.3
N.A.
88.1
75.9
N.A.
78.5
78.3
77.4
75.9
N.A.
68.2
67.3
N.A.
N.A.
P-Site Identity:
100
93.3
6.6
60
N.A.
6.6
66.6
N.A.
73.3
73.3
66.6
60
N.A.
60
66.6
N.A.
N.A.
P-Site Similarity:
100
93.3
20
80
N.A.
6.6
80
N.A.
93.3
86.6
86.6
86.6
N.A.
86.6
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
32.2
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
48.9
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
53.3
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
86.6
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
0
0
0
0
0
8
0
0
8
16
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
8
8
0
0
0
0
0
0
% C
% Asp:
0
0
0
31
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
16
0
8
54
0
0
0
0
0
77
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
8
0
0
0
0
8
% F
% Gly:
0
0
0
0
0
0
0
8
8
0
0
8
0
0
0
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
70
0
16
0
0
0
0
0
0
62
0
% I
% Lys:
24
0
0
0
0
0
8
8
77
0
0
0
0
0
8
% K
% Leu:
0
93
24
0
0
85
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
39
0
0
0
54
0
0
0
0
0
0
0
0
% M
% Asn:
16
0
0
8
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
8
8
0
85
0
0
0
0
% P
% Gln:
16
0
0
0
0
0
0
0
0
8
0
0
0
8
0
% Q
% Arg:
0
0
0
8
8
16
24
0
0
0
0
0
8
8
85
% R
% Ser:
24
0
0
0
0
0
0
62
0
0
0
70
0
0
0
% S
% Thr:
0
0
0
0
16
0
0
0
0
8
0
0
8
0
0
% T
% Val:
0
0
31
0
8
0
0
0
0
0
8
0
0
24
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
8
85
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _